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Valeria Bruno Selected Research

cinnabarinic acid

12/2020The Trace Kynurenine, Cinnabarinic Acid, Displays Potent Antipsychotic-Like Activity in Mice and Its Levels Are Reduced in the Prefrontal Cortex of Individuals Affected by Schizophrenia.
1/2017Cinnabarinic acid and xanthurenic acid: Two kynurenine metabolites that interact with metabotropic glutamate receptors.

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Valeria Bruno Research Topics

Disease

8Alzheimer Disease (Alzheimer's Disease)
01/2020 - 08/2002
7Schizophrenia (Dementia Praecox)
12/2020 - 08/2007
6Ischemia
01/2020 - 12/2008
4Neuroinflammatory Diseases
01/2021 - 07/2002
4Multiple Sclerosis
07/2020 - 07/2002
3Pain (Aches)
01/2022 - 10/2012
3Absence Epilepsy (Childhood Absence Epilepsy)
11/2020 - 02/2015
3Epilepsy (Aura)
01/2019 - 12/2008
3Parkinson Disease (Parkinson's Disease)
01/2017 - 08/2009
3Mental Disorders (Mental Disorder)
01/2017 - 12/2015
3Parkinsonian Disorders (Parkinsonism)
08/2015 - 01/2004
3Brain Ischemia (Cerebral Ischemia)
12/2008 - 03/2005
3Glioma (Gliomas)
08/2007 - 03/2003
2Chronic Pain
01/2022 - 01/2017
2Infarction (Infarctions)
01/2021 - 02/2009
2Autoimmune Diseases (Autoimmune Disease)
07/2020 - 01/2011
2Psychotic Disorders (Schizoaffective Disorder)
01/2019 - 03/2011
2Amyotrophic Lateral Sclerosis (Lou Gehrig's Disease)
01/2018 - 02/2015
2Middle Cerebral Artery Infarction (Middle Cerebral Artery Syndrome)
01/2017 - 04/2011
2Neuralgia (Stump Neuralgia)
01/2017 - 10/2012
2Neoplasms (Cancer)
01/2011 - 07/2005
2Temporal Lobe Epilepsy
12/2008 - 04/2007
2Neurodegenerative Diseases (Neurodegenerative Disease)
03/2008 - 05/2007
2Seizures (Absence Seizure)
04/2007 - 08/2005
2Hypoxia (Hypoxemia)
03/2007 - 08/2004
1Anhedonia
11/2021
1Diabetic Neuropathies (Diabetic Neuropathy)
01/2020
1Retinal Degeneration
11/2017
1Generalized Epilepsy
11/2017
1Major Depressive Disorder (Major Depressive Disorders)
01/2017
1Inflammation (Inflammations)
01/2017
1Disease Progression
01/2017
1Catalepsy
08/2015
1Adjustment Disorders (Adjustment Disorder)
06/2015
1Spinocerebellar Ataxias (Spinocerebellar Ataxia)
02/2015
1Autistic Disorder (Autism)
03/2014
1Angelman Syndrome (Syndrome, Angelman)
03/2014
1AIDS-Related Complex (ARC)
03/2014
1Relapsing-Remitting Multiple Sclerosis
01/2013
1Dyskinesias (Dyskinesia)
09/2012
1Central Nervous System Diseases (CNS Diseases)
01/2012

Drug/Important Bio-Agent (IBA)

14Metabotropic Glutamate Receptors (Metabotropic Glutamate Receptor)IBA
01/2021 - 03/2003
11Glutamic Acid (Glutamate)FDA Link
01/2019 - 07/2005
10Pharmaceutical PreparationsIBA
01/2019 - 07/2005
6LigandsIBA
01/2019 - 08/2007
4KynurenineIBA
12/2020 - 12/2015
4LY 341495IBA
10/2012 - 03/2003
4Amyloid beta-PeptidesIBA
03/2011 - 08/2002
3Freund's AdjuvantIBA
01/2022 - 10/2012
3Glial Cell Line-Derived Neurotrophic Factor (GDNF)IBA
01/2021 - 08/2009
3Antipsychotic Agents (Antipsychotics)IBA
12/2020 - 12/2015
3Endothelin-1 (Endothelin 1)IBA
01/2017 - 02/2009
3Proteins (Proteins, Gene)FDA Link
03/2014 - 03/2005
2cupric sulfide (CuS)IBA
11/2021 - 06/2015
2cinnabarinic acidIBA
12/2020 - 01/2017
2Analgesics (Analgesic Drugs)IBA
01/2017 - 10/2012
2Tryptophan (L-Tryptophan)FDA Link
01/2017 - 12/2015
2xanthurenic acidIBA
01/2017 - 12/2015
2Fingolimod Hydrochloride (FTY720)FDA Link
06/2015 - 01/2013
2Brain-Derived Neurotrophic Factor (BDNF)IBA
06/2015 - 04/2009
21- Methyl- 4- phenyl- 1,2,3,6- tetrahydropyridine (MPTP)IBA
09/2012 - 01/2004
2Kainic Acid (Kainate)IBA
12/2008 - 04/2007
1Chondroitin ABC LyaseIBA
01/2022
1CorticosteroneIBA
11/2021
1Sucrose (Saccharose)IBA
11/2021
1Mannose (D-Mannose)IBA
01/2021
1Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA
01/2021
1Interleukin-6 (Interleukin 6)IBA
01/2021
1Phosphates (Orthophosphate)IBA
01/2021
1Interleukin-4 Receptors (Interleukin 4 Receptor)IBA
01/2021
1N- cyclobutyl- 6- ((3- fluorophenyl)ethynyl)nicotinamideIBA
11/2020
1Hydrogen Sulfide (Sulfide, Hydrogen)IBA
07/2020
1GYY 4137IBA
07/2020
1EnzymesIBA
07/2020
1Macrophage Migration-Inhibitory FactorsIBA
01/2020
1CB1 Cannabinoid Receptor (CB1 Receptor)IBA
01/2020
1Acetylcysteine (Siran)FDA LinkGeneric
01/2020
1Glutamate Receptors (Glutamate Receptor)IBA
01/2019
1Sodium Glutamate (Accent)IBA
11/2017
1ThrombospondinsIBA
11/2017
1Immunoglobulin E (IgE)IBA
11/2017
1Acetylcarnitine (Alcar)IBA
01/2017
1Biomarkers (Surrogate Marker)IBA
01/2017
1Endothelium-Dependent Relaxing Factors (Endothelium Derived Relaxing Factor)IBA
01/2017
1Messenger RNA (mRNA)IBA
10/2015
1Haloperidol (Haldol)FDA LinkGeneric
08/2015
1Histone Deacetylases (Histone Deacetylase)IBA
06/2015
1Antidepressive Agents (Antidepressants)IBA
06/2015
1UbiquitinIBA
03/2014
1Ligases (Synthetase)IBA
03/2014
1Homer Scaffolding Proteins (Homer 1)IBA
03/2014
1Sphingosine-1-Phosphate ReceptorsIBA
01/2013
1Cysteine (L-Cysteine)FDA Link
10/2012
1Levodopa (L Dopa)FDA LinkGeneric
09/2012
1Estrogens (Estrogen)FDA Link
01/2012
1Transforming Growth Factors (Transforming Growth Factor)IBA
03/2011

Therapy/Procedure

4Analgesia
01/2022 - 10/2012
2Therapeutics
01/2011 - 08/2009
1Controlled Hypotension
01/2017
1Injections
10/2012